Having a large clinical trial portfolio means giving patients treatment options often not available anywhere else, and years before they become the standard of care. To learn more about Karmanos Cancer Institute clinical trials or to see if a trial is right for you, please call 1-800-KARMANOS (1-800-527-6266) or request an appointment below
  • A Phase 1 Study of RO7623066 Alone and in Combination in Patients with Advanced Solid Tumors

    Cancer Categories
    • Breast,Gastrointestinal (GI),Gynecologic
    Karmanos Trial ID
    • 2023-021
    NCT ID
    • NCT05240898
    Age Group
    • Adult
    Scope
    • National
    PhaseClick for Clinical Trial Phase DefinitionPhase I
    Includes initial studies to determine the metabolism and pharmacologic actions of drugs in humans, the side effects associated with increasing doses, and to gain early evidence of effectiveness; may include healthy participants and/or patients.
    • Phase I
    Principal Investigator
    • Ira
      Winer, M.D., Ph.D., FACOG

      Oncology - Gynecologic, Oncology - Surgical View Profile

    Objective:

    Primary Objective:

    • Determine the maximum tolerated dose
      (MTD) and the recommended Phase 2
      dose (RP2D) of KSQ-4279 alone and in
      combination in patients with advanced
      solid tumors

    Secondary Objectives:

    • Assess the safety and tolerability of
      KSQ-4279 alone and in combination in
      patients with advanced solid tumors
    • Characterize the PK profile of KSQ-
      4279 alone and in combination in
      patients with advanced solid tumors
    • Evaluate preliminary antitumor activity
      of KSQ-4279 alone and in combination
      in patients with advanced solid tumors
  • Locations

    Locations

    Karmanos Cancer Institute - Detroit Headquarters

    4100 John R
    Detroit, MI 48201
    Get Directions
    Phone: 800-527-6266

    Karmanos Cancer Institute at Weisberg Cancer Center - Farmington Hills

    31995 Northwestern Hwy
    Farmington Hills, MI 48334
    Get Directions
    Phone: 800-527-6266